THE CORRELATION OF LEFT VENTRICULAR MECHANICAL DISPERSION AND LEFT VENTRICULAR EJECTION FRACTION WITH QT DISPERSION IN END-STAGE RENAL DISEASE PATIENTS ON HEMODIALYSIS BEFORE AND AFTER DIALYSIS

Harry Pribadi, Agnes Lucia Panda, Benny Mulyanto Setiadi

Abstract


Background: Ventricular arrhythmias (VA) is common in dialytic patients. Left Ventricular Mechanical Dispersion (LVMD) could provide an inhomogeneous of left ventricular myocardium contraction lead to VA. Reduced Left Ventricular Ejection Fraction (LVEF) and QT Dispersion (QTd) are well-known VA predictors in dialytic patients. This study aimed to determine the relationship between LVMD and LVEF on QT dispersion in ESRD patients before and after dialysis.
Methods: This cross-sectional study was conducted in November 2021 - February 2022. All study subjects who met the inclusion criteria underwent history taking and physical examination including age, sex, body weight, body height, electrocardiography, echocardiography, and routine laboratory studies.
Results: Among 43 subjects, 24 (55.8%) were male, with mean age of 51,14±11,6 was conducted in this study. The most common comorbidities were hypertension (79%) and diabetes mellitus (44.19%). Pre-dialysis LVMD mean was 28.99±15.98 ms and significantly decrease to 24.16±15.77 ms after dialysis (p<0.05). There was insignificant decrease in the QTd value before dialysis with a mean 61.72±25.93 ms to 54.60±21.26 ms. There was no difference in the mean LVEF before dialysis (57.19±5.17%) and after dialysis (57.54±5.04%). There are no correlation between LVEF, LVMD and QTd variables before and after dialysis.
Conclusion: There was a significant decrease of LVMD after dialysis period, but there was no significant difference in the LVEF and QTd parameters. No correlation was found between QTd parameters, LVMD, or LVEF in ESRD patients on HD both before and after dialysis.

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Keywords


Sudden cardiac death; end-stage renal disease; hemodialysis; left ventricular mechanical dispersion; left ventricular ejection fraction; QT dispersion

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References


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DOI: https://doi.org/10.33508/jwm.v8i2.4152