REPORTING THE DETECTION RESULT OF SARS-CoV-2 ANTIBODY RAPID TEST OF COMPANY’S EMPLOYEES IN SURABAYA AND PASURUAN, INDONESIA

Mulya Dinata, Angelina Tulus, Evelyn Ongkodjodjo, Lukas Slamet Rihadi, Dewa Ayu Liona Dewi, Gabrielle Tjipta Joewana, Nurlita Wulansari

Abstract


Background: Coronavirus (CoV) is a large family of viruses that causes illnesses ranging from mild to severe symptoms. Coronavirus Disease (Covid-19) is a new type of virus that has never been indentified in humans before.
Methods: All antibody test methods and RT-PCR tests have an optimum time window in the incubation period or infection of a person. The antibody test method cannot be used as an early detection tool for people who are still on the first day of the incubation process. IgG and IgM antibody levels are still low on the first day of infection, even though the number of viral particles is very high at the beginning.
Result: Sars-Cov-2 (Covid-19) antibody examination sample was taken from Main Clinic of Sentra Medika Surabaya, from May to August 2020, with the age range of 18-65 old amounted to 1015 people. The number of samples with the age range of 40-49 is 404 people (39,90%), Production Department has 773 samples of people (76,16%), the number of security samples is 39 people (3,84%), and others have 109 samples of people (10,74%). The number of male samples is 666 people (65,62%) more than female 349 people (34,38%). Positive Covid-19 Antibody examination results for Office Department are IgM 3 people, IgG 3 people, and the total numbers are 6 people (21%). Positive Covid-19 Antibody examination results for the production department are IgM 14 people, IgG 1 person. So, the total numbers are 17 people (59%). The most positive Covid-19 antibody examination result is the production department namely 59% and including positive results for IgM and IgG. The condition above the production department has the most frequent because of the condition of employees including some companies which had overtime work or 2 shifts.
Conclusion: The highest number of Positive Covid-19 antibody examination result. The most department is the production department. The age range of 50-59 years old has a small number. At the time of being infected with Covid-19, IgG and IgM are negative, it needs time to get a positive examination result of IgG or IgM or both. The antibody examination method cannot be used as an early detection tool for Covid-19.

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Keywords


Covid-19, Antibody test, IgM, IgG

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References


Direktorat Jendral pencegahan dan Pengendalian Penyakit, Kementrian Kesehatan RI, 27 Maret 2020

Erlina Burhan, Covid-19 gejala klinis dan pengobatannya, Departemen pulmonology dan kedokteran Respirasi FKUI, 2019

WHO, 2019 novel Coronavirus (2019-nCov) strategic Preparedness and Response Plan. February 2020.

Pengurus Pusat Perhimpunan Dokter Spesialis Patologi Klinik dan Kedokteran Laboratorium Indonesia (PDS PatKLIn), Manajemen Spesimen dan Diagnosis Laboratorium Kasus Suspek 2019-nCoV.

Litbang Kompas, 5 Maret 2020

Budiman Tanuredjo., Lima Bulan pandemic, Catatan Politik dan hukum, Kompas, 1 Agustus 2020.

Surya.co.id., Update kasus virus Corona atau Covid-19 di kota Surabaya dan Jawa Timur, kamis 30 Juli 2020.

Adhi I.S., beda-alur-pemeriksaan-rapid-test-antibodi-dan-rapid-test- antigen?.https://health.kompas.com, 9 April 2020.

Kawal COVID-19 .Tim administrator situs KawalCOVID19.id. Perbandingan metode rapid test dan swab test dalam pendeteksian COVID-19, 27 April 2020.

Liang X., Feng Z., Li L., guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis and Management. People’s Medical Publishing house; 2020.

WHO., Tatalaksana klinis infeksi saluran pernapasan akut berat (SARI) suspek penyakit Covid-19. Panduan sementara; 13 Maret 2020.

Ardyanto T.D., Rapid Test Covid:Urgensi, Variasi dan Interpretasi. PERSI; 11 juni 2020

NIH(Nasional Institutes of Health), Coronavirus Disease 2019 (Covid-19) treatment Guaidelines. 2020.

Hattas A. W. Monitoring Gangguan Koagulasi pada perawatan Intensif Pasien dengan Covid-19; Webinar Hemostasis; 29 April 2020.

Saxena S.K. Corona Virus 2019 (Covid-19) Epidemiology, Pathogenesis, Diagnosis, and Therapeutics. Springer Nature, Singapore; 2020. Pages 95-107

Nardell E., Nathavitharana R.R. Airborne Spread of SARS-cOv-2 and a Potential Role For Air Disinfection. American Medical Association; June 6, 2020; 395; P. 1755.

Watson J. GP., Whiting P.F., Brush J.E. Interpreting a covid-19 test result, BMJ. 2020; 369; P.1-7.

J.J Deeks, J. Dinnes., Y Takwoingi, et.al. Antibody tests for identification of current and infection with SARS-COv-2 (Review). Cochrane Database of Systematic Review, 2020; P. 1-4.

Ward D., Explaining Wide Variations in Covid-19 Case Fatality Rates : What’s Raelly Going On ? Research Gate; April 2020; P. 5.

Ward D., Sampling Bias : Explaning Variations Age Distributions of Covid-19 Cases. Research Gate; May 2020; P. 8.

Liu K., Chen Y., Lin R., Review Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients. Journal of infection, 80 (2020), P. 14-18




DOI: https://doi.org/10.33508/jwm.v9i1.4631