THE USE OF BASEL SCORE IN EARLY DETECTION OF CORONARY LESION SEVERITY IN NON-ST SEGMENT ELEVATION MYOCARDIAL INFARCTION AND UNSTABLE ANGINA PECTORIS

Andrew Eka Pramudita Sunardi, Dewi Utari Djafar, Edmond Leonard Jim, Fima Lanra Fredrik Gerald Langi

Abstract


Early diagnosis of cardiac ischemia is crucial for effective management of acute myocardial infarction. The BASEL (Better Analysis of ST-segment Elevations and Depressions in a 12-leads-ECG) score has been shown to provide additional diagnostic value to the established electrocardiographic (ECG) criteria. This study aimed to evaluate the use of BASEL score to determine the severity of coronary lesions in patients with non-ST segment elevation acute coronary syndrome. This study used a cross-sectional approach and was conducted from January 2021 to January 2022.
From a total of 90 subjects, more than three-quarters were male, while the mean age was 60.3 years. The median BASEL score was 2.3 (1–4.2). GRACE 2.0 score had a mean of 97.3±26. The SYNTAX I score had a mean of 25±15.6, the SYNTAX II – PCI median score was 34.5 (25.9-42.4), and the SYNTAX II-CABG mean score was 23.4±11.9. The BASEL score showed a significant association with the SYNTAX I score both in univariate 2.60 (2.60-3.59), p<0.001, and in multivariate model 2.16 (0.99-3.34), p=0.001. The BASEL score appeared superior to the GRACE 2.0 score for lesion classification prediction according to the SYNTAX I AUC Z=3.29; p<0.001 for SYNTAX score of ≥33 and AUC Z=3.72, p<0.001 for SYNTAX score of >22. However, the SYNTAX II-PCI score, the classification ability of BASEL and GRACE scores did not differ AUC Z=1.02, p=0.306 for SYNTAX scores ≥33, and AUC Z=0.85, p=0.393 for SYNTAX score of >22.
The BASEL score is significantly associated with the SYNTAX I score and provide better discrimination than the GRACE 2.0 score in determining the severity of coronary lesion.

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Keywords


BASEL Score; non-ST segment myocardial infarction; unstable angina pectoris; SYNTAX score; GRACE score

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References


Sunjaya, AP., Sunjaya, AF., Priyana, A. Insights and challenges of Indonesia’s acute coronary syndrome telecardiology network: three-year experience from a single center and in west Jakarta Indonesia. TICATE 2018

Aditya, M., Wahyuni, CU., Isfandiari, MA. Risk factor analysis of recurrent acute coronary syndrome. Jurnal Berkala Epidemiologi 2018;6(3):192-199

Azab, AE., Elsayed, AS. Acute myocardial infarction risk factors and correlation of its markers with serum lipids. J Appl Biotechnol Bioeng 2017;3(4):00075

Ralapanawa, U., Kumarasiri, PV., Jayawickreme, KP., Kumarihamy, P., Wijeratne, Y., Ekanayake, M., et al. Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka. BMC Cardiovascular Disorders 2019;19:229

Grimm, K., Twerenbold, R., Abaecherli, R., Boeddinghaus, J., Nestelberger, T., Koechlin, L., et al. Diagnostic and prognostic value of ST-segment deviation scores in suspected acute myocardial infarction. European Heart Journal: Acute Cardiovascular Care 2020:1-12

Firdous, S., Malik, U. Clinical application of GRACE risk score in patients with acute coronary syndrome. Annals 2017;23(2)

Everett, CC., Fox, KA., Reynolds, C., Fernandez, C., Sharples, L., Stocken, DD., et al. Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalized with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomized registry-based trial. BMJ Open 2019;9:e032165

Huang, W., Fitzgerald, G., Goldberg, RJ., Gore, J., McManus, RH., Awad, H., et al. Performance of the GRACE risk score 2.0 simplified algorithm for predicting 1-year death after hospitalization for an acute coronary syndrome in a contemporary multiracial cohort. Am J Cardiol 2016

Zafar, F., Akbar, AM., Tariq, A., Masood, M. Correlation between GRACE and SYNTAX scores in patients with acute coronary syndrome. J Cardiovasc Dis 2018;14(3):64-67

Obeid, S., Frangieh, AH., Raber, L., Yousif, N., Gilhofer, T., Yamaji, K., et al. Prognostic value of SYNTAX score II in patients with acute coronary syndromes referred for invasive management: a subanalysis from the SPUM and COMFORTABLE AMI cohorts. Cardiology Research and Practice 2018

Sofidis G, Otountzidis N, Stalikas N, et al. Association of grace risk score with coronary artery disease complexity in patients with acute coronary syndrome. J Clin Med. 2021;10(10).

Ono M, Kawashima H, Hara H, et al. External validation of the GRACE risk score 2.0 in the contemporary all-comers GLOBAL LEADERS trial. Catheter Cardiovasc Interv. 2021;98(4):E513-E522.

Escaned J, Collet C, Ryan N, et al. Clinical outcomes of state-of-the-art percutaneous coronary revascularization in patients with de novo three-vessel disease: 1-year results of the SYNTAX II study. Eur Heart J. 2017;38(42):3124-3134.




DOI: https://doi.org/10.33508/jwm.v9i2.5060