Peranan Vaksinasi Human Papillomavirus (HPV) Sebagai Penatalaksanaan Pada Penderita Infeksi Human Immunodeficiency Virus (HIV), Bagian 1: Manifestasi Infeksi HIV Dan HPV

Dave Gerald Oenarta

Abstract


Human papillomavirus (HPV) and human immunodeficiency virus (HIV) both comprise global problems as these infections are widespread around the world and interplay with each other. HPV has many serotypes and it is known that serotypes 16 and 18 are the most common cause of cervical cancer. Cancer itself has been known to be strongly correlated to the host immune status. It is known that HPV infection indicates that the infected individuals are at risk of other sexually transmitted infections including HIV whilst HIV infection may increase the chance of someone to contract HPV and may propagate the HPV-related complication such as cancer. While there is no HIV vaccination yet in the market, HPV vaccination has become the norm to effectively prevent the acquisition of this virus. There are three available vaccine types in the market; the bivalent vaccine for HPV 16 and 18, the quadrivalent vaccine for HPV 6, 11, 16 and 18, and the most recent one the nonavalent vaccine for 9 different serotypes of the virus. Recent guidelines have recommended the use of HPV vaccines for HIV infected individuals both for the prevention of HPV infection and for the suppression of the increased HPV-related cancer incidence.

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Keywords


Human papillomavirus (HPV), human immunodeficiency virus (HIV), HPV vaccination.

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References


Markowitz LE, Liu G, Hariri S, Steinau M, Dunne EF, Unger ER. Prevalence of HPV After Introduction of the Vaccination Program in the United States. Pediatrics. 2016;137(3):e20151968.

Denny LA, Franceschi S, de Sanjosé S, Heard I, Moscicki AB, Palefsky J. Human papillomavirus, human immunodeficiency virus and immunosuppression. Vaccine. 2012;30 Suppl 5:F168-174.

Monie A, Hung CF, Roden R, Wu TC. Cervarix: a vaccine for the prevention of HPV 16, 18-associated cervical cancer. Biologics. 2008;2(1):97-105.

Siddiqui MA, Perry CM. Human papillomavirus quadrivalent (types 6, 11, 16, 18) recombinant vaccine (Gardasil): profile report. BioDrugs. 2006;20(5):313-316.

Toft L, Tolstrup M, Storgaard M, Ostergaard L, Søgaard OS. Vaccination against oncogenic human papillomavirus infection in HIV-infected populations: review of current status and future perspectives. Sex Health. 2014;11(6):511-523.

Merati KTP. HIV sebagai Penyebab AIDS. In: Disertasi Subtipe HIV-1 di Beberapa Daerah di Indonesia dan Perannya Sebagai Petunjuk Dinamika Epidemi HIV. Denpasar: FK Universitas Udayana; 2008:14-18.

Moir S, Chun T, Fauci A. Immunology and Pathogenesis of Human Immunodeficiency Virus Infection. In: Holmes K, Sparling P, Stamm W, et al., eds. Sexually Transmitted Diseases. 4th ed. New York: McGraw-Hill; 2008:341-359.

Harrington PR, Swanstrom R. The Biologi of HIV, SIV, and Other Lentiviruses. In: Holmes KK, Sparling PF, Stamm WE, et al., eds. Sexually Transmitted Diseases. 4 ed. New York: McGraw-Hill; 2008:323-341.

Duarsa NW. Infeksi HIV dan AIDS. In: Daili SF, Makes WIB, Zubier F, eds. Infeksi Menular Seksual. 4 ed. Jakarta: Balai Penerbit FKUI; 2009:146-159.

Workowski KA, Bolan GA, Prevention CfDCa. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015;64(RR-03):1-137.

Dochez C, Bogers JJ, Verhelst R, Rees H. HPV vaccines to prevent cervical cancer and genital warts: an update. Vaccine. 2014;32(14):1595-1601.

Wang CJ, Palefsky JM. Human Papillomavirus (HPV) Infections and the Importance of HPV Vaccination. Curr Epidemiol Rep. 2015;2(2):101-109.

Patel H, Wagner M, Singhal P, Kothari S. Systematic review of the incidence and prevalence of genital warts. BMC Infect Dis. 2013;13:39.

Cone MM, Whitlow CB. Sexually transmitted and anorectal infectious diseases. Gastroenterol Clin North Am. 2013;42(4):877-892.

Yanofsky VR, Patel RV, Goldenberg G. Genital warts: a comprehensive review. J Clin Aesthet Dermatol. 2012;5(6):25-36.

Doorbar J. Latent papillomavirus infections and their regulation. Curr Opin Virol. 2013;3(4):416-421.

Blomberg M, Friis S, Munk C, Bautz A, Kjaer SK. Genital warts and risk of cancer: a Danish study of nearly 50 000 patients with genital warts. J Infect Dis. 2012;205(10):1544-1553.

Gormley RH, Kovarik CL. Human papillomavirus-related genital disease in the immunocompromised host: Part I. J Am Acad Dermatol. 2012;66(6):867.e861-814; quiz 881-862.

Workowski KA. Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines. Clin Infect Dis. 2015;61 Suppl 8:S759-762.

Marrazzo JM, Gorgos LM. Emerging Sexual Health Issues Among Women Who Have Sex with Women. Curr Infect Dis Rep. 2012.

Winer RL, Hughes JP, Feng Q, et al. Early natural history of incident, type-specific human papillomavirus infections in newly sexually active young women. Cancer Epidemiol Biomarkers Prev. 2011;20(4):699-707.

Sundström K, Eloranta S, Sparén P, et al. Prospective study of human papillomavirus (HPV) types, HPV persistence, and risk of squamous cell carcinoma of the cervix. Cancer Epidemiol Biomarkers Prev. 2010;19(10):2469-2478.

Cuzick J, Arbyn M, Sankaranarayanan R, et al. Overview of human papillomavirus-based and other novel options for cervical cancer screening in developed and developing countries. Vaccine. 2008;26 Suppl 10:K29-41.

Gillison ML, Broutian T, Pickard RK, et al. Prevalence of oral HPV infection in the United States, 2009-2010. JAMA. 2012;307(7):693-703.

Chaturvedi AK, Anderson WF, Lortet-Tieulent J, et al. Worldwide trends in incidence rates for oral cavity and oropharyngeal cancers. J Clin Oncol. 2013;31(36):4550-4559.

Combes JD, Franceschi S. Role of human papillomavirus in non-oropharyngeal head and neck cancers. Oral Oncol. 2014;50(5):370-379.

Tugizov S, Herrera R, Veluppillai P, Greenspan D, Palefsky J. HIV-facilitated paracellular penetration of HPV into mucosal epithelium. XIX International AIDS Conference; 2012; Washington DC, USA.

Houlihan CF, Larke NL, Watson-Jones D, et al. Human papillomavirus infection and increased risk of HIV acquisition. A systematic review and meta-analysis. AIDS. 2012;26(17):2211-2222.

Chin-Hong PV, Husnik M, Cranston RD, et al. Anal human papillomavirus infection is associated with HIV acquisition in men who have sex with men. AIDS. 2009;23(9):1135-1142.




DOI: https://doi.org/10.33508/jwm.v5i2.2206