Hyper-coagulation and The Used of Anticoagulant for Patient with COVID-19

Alyssa Claudia V. Gunawan, Bernadette Dian Novita

Abstract


Coronavirus SARS-CoV-2 (COVID-19) infection has become a global infection with high mortality and morbidity rate. The pathophysiology of COVID-19 has not yet clear but associated with increasing proinflammatory cytokines and chemokines that leads to cytokine storm. Cytokine storm leads to increasing coagulation that defined by increasing D-dimer, Prothrombin Time (PT), and activated partial thromboplastin time (aPTT). The use of anticoagulant in patient with COVID-19 decrease the mortality rate and become one of the recommended therapy.

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Keywords


COVID-19; Hyper-coagulation; Anticoagulant

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References


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DOI: https://doi.org/10.33508/jwm.v6i2.2787