ASSOCIATION OF LONG-TERM MEDITERRANEAN DIETARY PATTERN AND DEPRESSIVE MOOD IN OLDER ADULTS: A SYSTEMATIC REVIEW OF COHORT STUDIES
Abstract
Depression is a significant global health concern that occurs frequently among individuals aged 65 and older. In addition to pharmacological therapy and psychotherapy, dietary interventions play a crucial role in the multifactorial, biopsychosocial treatment of psychiatric disorders and could be used as a potential therapeutic target. Increasing evidence is emerging about the important role of the Mediterranean diet (MeDi) in the pathophysiology of mood disorders, particularly depression. This systematic review aims to assess whether long-term adherence to MeDi affects depressive symptoms in the elderly based on published cohort studies. Literature searches are conducted on several databases (PubMed, ProQuest, ScienceDirect, and Google Scholar) with keywords related to “Mediterranean diet”, “depression” and “elderly”. The research was done based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. Studies were then screened based on the inclusion criteria, with the result of 3 included cohort studies out of 5,123 identified studies. Study characteristics were extracted and the risk of bias was assessed with the Joanna Briggs Institute Critical Appraisal Checklist for each study. Based on the study analysis, the relationship between adherence to the Mediterranean diet and depression in elderly over time is inconclusive due to conflicting results and limited studies.
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DOI: https://doi.org/10.33508/jwmj.v6i4.5993
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