The Effectiveness Of Saline Nasal Spray Therapy On Changes In Nasal Mucociliary Transport Time In Patient With Allergic Rhinitis

I Komang A Subagiarta, Wiyono Hadi, Endang Isbandiati

Abstract


Introduction: Treatment for allergic rhinitis as a disease that can impact on the quality of life, work productivity, school performance, and disturbances in the physiological function of the nose with recurring symptoms need more effective treatment. Nasal wash solution with isotonic saline in nasal spray method (Saline Nasal Spray) is known to reduce the symptoms of allergic rhinitis by clearing secretions, reduces edema, and remove harmful ingredients that go along with breathing air. The purpose of this study ledge used for the effectiveness of Saline Nasal Spray to changes in nasal mucociliary transport time patients with allergic rhinitis. Methods: Experimental research of pre-post test with control group design. Mucociliary transport time was measured using the saccharine test 20 samples in the group treated with saline nasal spray treatment and 20 samples in the control group without saline nasal spray. Result: Based on the analysis, Mann-Whitney for the treatment group and the control group obtained significant results p = 0.000 (p <0.05), which indicates that there are significant differences in nasal mucociliary transport time after treatment for seven days. The use of saline nasal spray as adjunctive therapy in the treatment of allergic rhinitis were able to improve nasal mucociliary clearance time is faster than just treatment with standard therapy. Mean of mucociliary transport time before treatment in the treatment group was 10.57 (SD ±4,69) minutes and 9.05 (SD ±4,36) minutes in the control group. Mean of mucociliary transport time after seven days of therapy in the treatment group was 6.22 (SD ±3,53) minutes and the control group was 6.42 (SD ±3,94) minutes. The mean improvement of mucociliary transport time obtained in the treatment group was 4.53 (SD ± 1,51) minutes and the control group was 3.00 (SD ± 1,54) minute. Conslusion: Adjunctive therapy with saline nasal spray in patients with allergic rhinitis has a better effect on the measurement of mucociliary transport time than without the use of saline nasal spray.

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References


Bousquet et al. 2008. European Journal of Allergy and Clinical Immunology Allergy. Supplement 86. Volume 63. Hal 55-61.

Diunduh dari http://www.whiar.org/docs/ARIA_WR_08_View_WM.pdf diakses pada 8 februari 2016

Nurcahyo, H. & Eko, V. 2009. Rinitis Alergi Sebagai Salah Satu Faktor Risiko Rinosinusitis Maksilaris Kronik. Yogyakarta: Universitas Gajah Mada.

Delfitri M. 2010. Waktu Bersihan Mukosiliar pada Pasien Rinosinusitis

Kronis. Majelis Kedokteran Indonesia: vol. 60, no. 11, hal. 518. Diunduh dari

http://indonesia.digitaljournals.org/index.php/idnmed/article/viewFile/752/748 diakses pada 8 februari 2016.

Hwang PH, Abdalkhani A.2009. Embriology, anatomy and physiology of nose and paranasal sinuses. Dalam: Snow JB, Wackym PA, editor. Ballenger’s

otolaryngology, head and neck surgery. Edisi ke-17. Shelton: BC Decker Inc; 2009. h.455-63.

Mc Caffrey TV, Remington WJ. 2000. Nasal function and evaluation. Dalam: Byron J. Bailey, editor. Head & neck surgery otolaryngology. Edisi ke-2. Philadelphia: Lipponcott-Raven; 2000.h.333- 48.

Sun SS.2000. Evaluation of nasal mucociliary clearance function in allergic rhinnitis patients with Technetium 99MLabeled Macro- aggregated Albumin Rhinoscintigraphy. Ann Otol Rhinol Laryngol. 2002;111:77-9.

Cohen NA. 2006. Sinonasal mucociliary clearance in health and di- sease. Ann Otol Rhinol Laryngol Suppl. 2006;196:20-6.

Prathibha et al. 2014. Measurement of nasal mucociliary clearance. Clin Res Pulmonal 2(2): 1019. Diunduh dari http://www.jscimedcentral.com/Pulmonolog y/pulmonology-2-1019.pdf diakses pada 8 Februari 2016.

Chang CC, Incaudo GA, and Gershwin ME, editors. 2014. Diseases of the sinuses 2st edition. New York: Springer. 2014

Ballenger JJ, 1994, Aplikasi Klinis Anatomi dan Fisiologi Hidung dan Sinus Paranasal dalam Penyakit Telinga, Hidung, Tenggorok, Kepala dan Leher. Jilid satu. Edisi 13. Binarupa Aksara. Jakarta. hal: 1-25.

Onerci MT, editor. Nasal physiology and nasal pathophysiology of nasal disorder. Heidelberg NY : Springer. 2013. hal : 1-25.

Sumarwan I, Strategi Rasional Pengelolaan Rinitis Alergis Perenial : Ditinjau Dari Aspek Mediator, Sitokin dan Molekul Adhesi. Makalah Simposium Allergic and Quality Of Life : Their Clinical Implications

In 21st Century. (2003).Fakultas Kedokteran Unpad, Bandung.:17.

Sumarman I., 2001. Patofisiologi Dan Prosedur Diagnostik Rhinitis Alergi. Di dalam Kumpulan Makalah Simposium Current and Future Approach in the Treatment of Allergic Rhinitis. Jakarta. Hal. 14-18.

Immanuel E.S. 2010. Perbedaan Waktu Transprtasi Mukosiliar Hidung Pada Penderita Rinosinusitis Kronis Setelah Dilakukan Bedah Sinus Endoskopik Fungsional Dengan Adjuvan Terapi Cuci Hidung Cairan Isotonik NaCl 0,9% Dibandingkan Cairan Hipertonik NaCl 3%. Universitas Sumatra Utara. Tesis. Diunduh dari http://repository.usu.ac.id/bitstream/1234567

/25985/5/Chapter%20I.pdf diakses tanggal 10 februari.

Irawati N, Kasakeyan E, Rusmono N. Buku Ajar Ilmu Kesehatan Telinga Hidung dan Tenggorok Kepala Leher : Rinitis Alergi. Edisi 7. Jakarta: Balai Penerbit FKUI. 2012. hal : 106-107

Lim D. Childhood Allergies: All You Need To Know About Your Child’s Allergy. Jakarta : Tim Indeks. 2013. Hal : 56-60




DOI: https://doi.org/10.33508/jwmj.v1i2.2017

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